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KMID : 1147720200130050167
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Journal of Acupuncture and Meridian Studies
2020 Volume.13 No. 5 p.167 ~ p.168
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Herbal Transformation by Fermentation
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Son Chang-Gue
Lee Sam-Keun
Choi In-Kyu
Jang Eun-Su
Bang Kee-Jung
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Abstract
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We herein show a dramatic change of herbal properties of the composition as well as function via fermentation of Cynanchi atrati Radix (family Asclepiadaceae). Cynanchi atrati Radix showed a high cytotoxicity against B16-F10 melanoma cell line, but the function of Cynanchi atrati Radix was completely changed into anti-melanin activity at very low concentration after Lactobacillus -fermentation. In addition, the compounds were drastically changed as shown in HPLC-based profile. Furthermore, this transformation has been achieved by only Lactobacillus -fermentation. This study proposes an strategy which we need to consider in the herb-derived material researches including pharmacopuncture.
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KEYWORD
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cynanchi atrati Radix, fermentation, herbal, lactobacillus
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